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Irreversible electroporation for liver cancer immunotherapy: A pilot study


To determine if treatment with High-Frequency Irreversible Electroporation (H-FIRE), which uses electrical pulses to destroy cancer cells, can cause an immune response in dogs with liver cancer.

Study Progress Update

We have completed enrollment for this study. Thank you to all those who participated.

High-frequency irreversible electroporation (H-FIRE) uses high-frequency bipolar electric pulses to destabilize cancer cell membranes and induce cell death. Cell death and tumor ablation following H-FIRE treatment activates the local innate immune system to further aid in the destruction of cancer cells.

In partnership with Virginia Tech’s Department of Biomedical Engineering and Mechanics, we continue studies in veterinary patients across a variety of tumor types. Researchers hope to continue this work with a new round of funding in 2020.


If you have questions about your participation in the study or about the study results, please contact us:

Ms. Mindy Quigley, Clinical Trials Coordinator
Office Phone: 540-231-1363 | Email: