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Hehuang “David” Xie, PhD

Professor
  • Epigenomics and Computational Biology
David Xie
Department of Biomedical Sciences and Pathobiology
VA-MD College of Veterinary Medicine
Virginia Tech
205 Duck Pond Drive
Blacksburg, VA 24061

Ph.D., Genetics Program, 2003
The University of Iowa
Iowa City, IA

Master of Science, Computer Science, 2003
The University of Iowa
Iowa City, IA

Master of Science, 1997
Shanghai Institute of Cell Biology
Chinese Academy of Science

Bachelor of Science, Genetics, 1994
Sichuan University
China

  • Neuro-epigenetics
  • Cancer and stem cell epigenomics
  • Computation biology and bioinformatics
  • Biotechnology and systems biology
  • Our group is particularly interested in strategies to assess epigenetic variation within and between cell populations, and to reveal transcription factors and gene networks controlling epigenetic dynamics during normal development and diseases. The term “epigenetic” mainly refers to histone modifications and DNA methylation, which are alternative ways to control gene expression while maintaining the nucleotide sequence of the genome. In other words, epigenetic changes allow cells with identical genomic content to demonstrate distinct phenotypes.
  • Learn more about research in Dr. Xie's Epigenomics and Computational Biology Laboratory.

2021–present
Professor

Department of Biomedical Sciences and Pathobiology
Virginia-Maryland College of Veterinary Medicine
Virginia Tech
Blacksburg, VA

2021–present
Professor
Fralin Life Sciences Institute
Virginia Tech
Blacksburg, VA

2016–2021
Associate Professor

Department of Biomedical Sciences and Pathobiology
Virginia-Maryland College of Veterinary Medicine
Virginia Tech
Blacksburg, VA

2016–2021
Associate Professor

Biocomplexity Institute of Virginia Tech
Department of Biological Sciences
Virginia Tech
Blacksburg, VA

2012–2016
Research Associate Professor

Biocomplexity Institute of Virginia Tech
Department of Biological Sciences
Virginia Tech
Blacksburg, VA

2005–2012
Research Assistant Professor

Cancer Biology and Epigenomics Program
Children's Memorial Research Center
Department of Pediatrics, Feinberg School of Medicine
Northwestern University
Evanston, IL

2004–2005
Post/Doctoral Research Associate

The University of Minnesota
Advisor: Dr. Scott C. Fahrenkrug
Minneapolis, MN

2003–2004
Post/Doctoral Research Associate

The University of Iowa
Advisor: Dr. Bento Soares
Iowa City, IA

1998–2003
Graduate Research Assistant

The University of Iowa
Advisor: Dr. Bento Soares
Iowa City, IA

  • Member, International Society of Computational Biology