Qi Ye, MS, PhD

MS & PhD, Pharmacology and Toxicology, 2018
Northeastern University
Boston, MA

BS, Pharmacy, 2012
Central South University
Hunan, China

• Defining the role of tumor-associated astrocytes in regulating vascular function and leveraging this knowledge to enhance brain penetrance of anticancer therapeutics.
• Determining the temporal and spatial roles of tumor-associated astrocytes in lipid metabolism and their implications for dietary and pharmacologic interventions.
• Elucidating pH-dependent, tumor-intrinsic signaling pathways regulated by tumor-associated astrocytes.

2026–present
Assistant Professor, Biomedical Sciences and Pathobiology at VMCVM
Assistant Professor, Fralin Biomedical Research Institute at VTC
Fralin Biomedical Research Institute of Virginia Tech
Washington, DC

2018–2025
Postdoctoral Fellow
Baylor College of Medicine
Houston, TX

• Ye Q, Madamba C, Woo J, Choy TJ, Cristobal CD, Spjut C, Wheeler K, Smith J, Shin D, Latha K, Harmanci A, Yalamanchili HK, Gallo M, Kim Y, Rao G, Deneen B, Lee HK. Ischemic stroke drives glioma progression by remodeling tumor-associated astrocytes (Under revision).
  
• Ye Q, Jo J, Wang C, Oh H, Choy TJ, Kim K, Alessandro DA, Reshetnyak YK, Jung SY, Chen Z, Marrelli SP, Lee HK (2024). Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation. Cell Reports, 28;43(5):114193 (PMID: 38709635)
• Chung H*, Ye Q*, Park Y, Lanza I, Oglesbee D, Kanca O, Tattikota S, Zuo Z, Perrimon N, Lee HK, Hugo J. Bellen (2023). Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation. Cell Metabolism. 35(5):855-874.e5 (PMID: 37084732)
• Ye Q, Trivedi M, Zhang Y, MarK B, Alsulimani H, Chang J, Maher T, Deth R, Kim J (2019). Brain iron loading impairs DNA methylation and alters GABAergic function in mice. FASEB. 33(2):2460-2471 (PMID: 30277817)

• Ye Laboratory

• Dean's Award of Excellence, the Graduate School of Biomedical Sciences, Baylor College of Medicine
• K99 Pathway to Independence Awards, Natinal Cancer Institute, National Institutes of Health
• The Zoghbi Scholar Award, Neurological Research Institute, Texas Children's Hospital Marvin and Gloria Fishman Trainee Endowed Fund Travel Scholarship, Texas Children's Hospital The Young Investigator's Educational Enhancement (YIEE), American Society of Neurochemistry, Virtual meeting
• Best Oral Presentation (5 out of 140), Pediatric Research Symposium, Texas Children's Hospital, Houston, TX
• The John L. Neumeyer Research Achievement Award (1 graduate student per year), Northeastern University, Boston, MA
• Poster of Distinction by the Programming Committee of the Gastrointestinal & Liver Section of the American Physiology Society, San Diego, CA
• Health Science Poster Award Winner (co-author), Research, Innovation, and Scholarship Expo (RISE), Boston, MA
• Xiangya Medical School outstanding undergraduate thesis (8 in 70), Central South University, China
• Outstanding graduates (3 in 70), Central South University, China
• Scholarship for top undergraduate students in the pharmaceutical science department (3 in 70), Central South University, China
• National Merit Scholarship (0.2% nationwide), Central South University, China